The NF Kappa B-p65 Monoclonal Antibody from Bioassay Technology Laboratory is a Mouse Monoclonal antibody. This antibody recognizes Human, and Mouse antigen. The NF Kappa B-p65 Monoclonal Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene